When it doesn't work

The failures people actually hit, with fixes ordered cheapest-first in quality terms rather than alphabetically.

ComfyUI runs out of memory
A diffusion pipeline is several models at once, and the text encoder is usually the one to move.
Ollama is slower than expected
Usually the model didn't fully fit, and Ollama ran it anyway across GPU and system RAM.
CUDA out of memory
The model, its KV cache and the runtime's working buffers don't fit in VRAM together.
It loaded, but generation is painfully slow
Part of the model is in system RAM. Spilling costs 5–20×, not 10%.
The GGUF file won't load
Your runtime is older than the model's architecture, or the file is a partial download.