Instinct MI250X
Instinct MI250X has 128 GB of VRAM at 3277 GB/s — about 119.04 GiB usable after driver and compositor overhead. 2091 of 2118 indexed models fit at 8K context with f16 KV.
What fits at 8K context
| Model | Best quant | Params | Weights● | KV● | Total in memory◐ | Headroom◐ | tok/s◐ |
|---|---|---|---|---|---|---|---|
| MiMo-V2-FlashMoEKV unresolved | I1-IQ3_XS | 310B | 117.12 GiB | 0.94 GiB | 119.01 GiB | 0.03 GiB | 92±37% |
| Qwen3.5-397B-A17BMoE | UD-IQ2_M | 403B | 117.81 GiB | 0.23 GiB | 118.99 GiB | 0.05 GiB | 108±37% |
| command-a-plus-05-2026-bf16MoE | Q4_0 | 219B | 117.42 GiB | 0.67 GiB | 118.99 GiB | 0.05 GiB | 74±37% |
| Mistral-Small-4-119B-2603MoE | Q8_0 | 119B | 117.79 GiB | 0.18 GiB | 118.89 GiB | 0.15 GiB | 97±37% |
| Trinity-Large-PreviewMoE | IQ2_M | 399B | 116.50 GiB | 1.26 GiB | 118.69 GiB | 0.35 GiB | 103±37% |
| Trinity-Large-TrueBaseMoE | IQ2_M | 399B | 116.50 GiB | 1.26 GiB | 118.69 GiB | 0.35 GiB | 103±37% |
| Step-3.7-Flash | UD-Q4_K_M | 201B | 113.71 GiB | 4.03 GiB | 118.66 GiB | 0.38 GiB | 18±26.5% |
| DeepSeek-Coder-V2-Instruct-0724MoE | IQ4_XS | 236B | 116.94 GiB | 0.53 GiB | 118.41 GiB | 0.63 GiB | 90±37% |
| DeepSeek-V2.5MoE | IQ4_XS | 236B | 116.94 GiB | 0.53 GiB | 118.41 GiB | 0.63 GiB | 90±37% |
| DeepSeek-Coder-V2-InstructMoE | IQ4_XS | 236B | 116.94 GiB | 0.53 GiB | 118.41 GiB | 0.63 GiB | 90±37% |
| grok-2MoE | IQ3_M | 270B | 115.25 GiB | 2.00 GiB | 118.29 GiB | 0.75 GiB | 32±37% |
| GLM-4.5MoE | UD-IQ2_M | 358B | 114.03 GiB | 2.88 GiB | 117.85 GiB | 1.19 GiB | 72±37% |
| GLM-4.7MoE | UD-IQ2_M | 358B | 114.03 GiB | 2.88 GiB | 117.85 GiB | 1.19 GiB | 72±37% |
| Qwen3.5-REAP-262B-A17BMoE | Q3_K_M | 262B | 116.42 GiB | 0.23 GiB | 117.60 GiB | 1.44 GiB | 99±37% |
| GLM-4.6MoE | UD-IQ2_M | 357B | 113.56 GiB | 2.88 GiB | 117.37 GiB | 1.67 GiB | 72±37% |
| step-3.5-flash | Q4_K_L | 199B | 112.07 GiB | 4.03 GiB | 117.03 GiB | 2.01 GiB | 18±26.5% |
| Ornith-1.0-397BMoE | UD-IQ2_M | 397B | 115.83 GiB | 0.23 GiB | 117.02 GiB | 2.02 GiB | 109±37% |
| Llama-3_1-Nemotron-51B-Instruct | F16 | 51.5B | 95.94 GiB | 20.00 GiB | 116.98 GiB | 2.06 GiB | 18±26.5% |
| gpt-oss-120b-abliteratedMoE | Q8_0 | 117B | 115.76 GiB | 0.31 GiB | 116.96 GiB | 2.08 GiB | 98±37% |
| MiniMax-M2.7MoE | IQ4_XS | 229B | 114.00 GiB | 1.94 GiB | 116.82 GiB | 2.22 GiB | 87±37% |
| MiniMax-M2.1MoE | IQ4_XS | 229B | 113.78 GiB | 1.94 GiB | 116.60 GiB | 2.44 GiB | 87±37% |
| MiniMax-M2MoE | IQ4_XS | 229B | 113.78 GiB | 1.94 GiB | 116.60 GiB | 2.44 GiB | 87±37% |
| MiniMax-M2.5MoE | IQ4_XS | 229B | 113.53 GiB | 1.94 GiB | 116.35 GiB | 2.69 GiB | 88±37% |
| Hermes-4-405B | IQ2_XS | 406B | 111.15 GiB | 3.94 GiB | 116.27 GiB | 2.77 GiB | 18±26.5% |
| Hermes-3-Llama-3.1-405B | IQ2_XS | 406B | 111.15 GiB | 3.94 GiB | 116.27 GiB | 2.77 GiB | 18±26.5% |
| Qwen3-235B-A22B-abliteratedMoE | I1-Q3_K_L | 235B | 113.46 GiB | 1.47 GiB | 115.86 GiB | 3.18 GiB | 73±37% |
| Llama-4-Maverick-17B-128E-InstructMoEKV unresolved | UD-IQ1_S | 402B | 112.48 GiB | 1.50 GiB | 114.90 GiB | 4.14 GiB | 112±37% |
| Trinity-Large-ThinkingMoE | IQ2_S | 399B | 112.03 GiB | 1.26 GiB | 114.22 GiB | 4.82 GiB | 106±37% |
| Solar-Open2-250BMoE | Q3_K_M | 250B | 111.63 GiB | 1.50 GiB | 114.06 GiB | 4.98 GiB | 96±37% |
| Llama-3_3-Nemotron-Super-49B-v1_5 | BF16 | 49.9B | 92.89 GiB | 20.00 GiB | 113.94 GiB | 5.10 GiB | 18±26.5% |
| Valkyrie-49B-v2.1 | BF16 | 49.9B | 92.89 GiB | 20.00 GiB | 113.94 GiB | 5.10 GiB | 18±26.5% |
| Llama-3_3-Nemotron-Super-49B-v1 | BF16 | 49.9B | 92.89 GiB | 20.00 GiB | 113.94 GiB | 5.10 GiB | 18±26.5% |
| GLM-4.7-REAP-218B-A32BMoE | IQ4_XS | 218B | 110.09 GiB | 2.88 GiB | 113.91 GiB | 5.13 GiB | 61±37% |
| Nex-N2-ProMoE | IQ2_S | 397B | 112.23 GiB | 0.23 GiB | 113.42 GiB | 5.62 GiB | 112±37% |
| MiniMax-M2.7-BF16-ultra-uncensored-hereticMoE | Q3_K_L | 229B | 110.22 GiB | 1.94 GiB | 113.05 GiB | 5.99 GiB | 89±37% |
| GLM-4.6-REAP-268B-A32BMoE | Q3_K_S | 269B | 108.47 GiB | 2.88 GiB | 112.29 GiB | 6.75 GiB | 68±37% |
| GLM-4.5-AirMoE | Q8_0 | 110B | 109.39 GiB | 1.44 GiB | 111.75 GiB | 7.29 GiB | 75±37% |
| GLM-4.5-Air-DerestrictedMoE | Q8_0 | 110B | 109.39 GiB | 1.44 GiB | 111.75 GiB | 7.29 GiB | 75±37% |
| GLM-4.6-Derestricted-v3MoE | IQ2_M | 357B | 107.14 GiB | 2.88 GiB | 110.96 GiB | 8.08 GiB | 75±37% |
| Qwen3-Coder-REAP-363B-A35BMoE | UD-IQ1_M | 363B | 107.85 GiB | 1.94 GiB | 110.72 GiB | 8.32 GiB | 72±37% |
| dots.llm1.instMoE | Q5_K_M | 143B | 101.84 GiB | 7.75 GiB | 110.52 GiB | 8.52 GiB | 60±37% |
| MiniMax-M3MoE | IQ2_XXS | 427B | 108.60 GiB | 0.94 GiB | 110.46 GiB | 8.58 GiB | 98±37% |
| Mixtral-8x22B-v0.1MoE | Q6_K | 141B | 107.60 GiB | 1.75 GiB | 110.31 GiB | 8.73 GiB | 34±37% |
| DeepSeek-V4-FlashMoE | UD-IQ3_S | 291B | 109.25 GiB | 0.06 GiB | 110.26 GiB | 8.78 GiB | 112±37% |
| MiniMax-M2.1-REAP-139B-A10BMoE | I1-Q6_K | 139B | 106.40 GiB | 1.94 GiB | 109.23 GiB | 9.81 GiB | 79±37% |
| m51Lab-MiniMax-M2.7-REAP-139B-A10BMoE | Q6_K | 139B | 106.40 GiB | 1.94 GiB | 109.23 GiB | 9.81 GiB | 79±37% |
| DeepSeek-V4-Flash-0731MoE | UD-IQ3_S | 304B | 108.10 GiB | 0.06 GiB | 109.11 GiB | 9.93 GiB | 113±37% |
| Llama-4-Scout-17B-16E-InstructMoEKV unresolved | Q8_0 | 109B | 106.67 GiB | 1.50 GiB | 109.09 GiB | 9.95 GiB | 76±37% |
| MiMo-V2.5MoEKV unresolved | UD-IQ3_S | 311B | 106.98 GiB | 0.94 GiB | 108.86 GiB | 10.18 GiB | 99±37% |
| NVIDIA-Nemotron-3-Super-120B-A12B-BF16MoE | UD-Q6_K | 124B | 106.87 GiB | 0.69 GiB | 108.45 GiB | 10.59 GiB | 92±37% |
| GLM-4.6VMoE | Q8_0 | 108B | 105.81 GiB | 1.44 GiB | 108.17 GiB | 10.87 GiB | 77±37% |
| Qwen3-VL-235B-A22B-ThinkingMoE | Q3_K_M | 236B | 104.72 GiB | 1.47 GiB | 107.13 GiB | 11.91 GiB | 77±37% |
| Qwen3-VL-235B-A22B-InstructMoE | Q3_K_M | 236B | 104.72 GiB | 1.47 GiB | 107.13 GiB | 11.91 GiB | 77±37% |
| Qwen3-235B-A22BMoE | Q3_K_M | 235B | 104.72 GiB | 1.47 GiB | 107.13 GiB | 11.91 GiB | 77±37% |
| Qwen3-235B-A22B-Thinking-2507MoE | Q3_K_M | 235B | 104.72 GiB | 1.47 GiB | 107.13 GiB | 11.91 GiB | 77±37% |
| Qwen3-235B-A22B-Instruct-2507MoE | Q3_K_M | 235B | 104.72 GiB | 1.47 GiB | 107.13 GiB | 11.91 GiB | 77±37% |
| Qwen3.5-REAP-212B-A17BMoE | IQ4_XS | 212B | 105.39 GiB | 0.23 GiB | 106.58 GiB | 12.46 GiB | 101±37% |
| Gemma-4-Dark-Gemistry-31B | Q8_0 | 32.7B | 102.98 GiB | 2.42 GiB | 106.38 GiB | 12.66 GiB | 20±26.5% |
| c4ai-command-r-plus-08-2024 | Q8_0 | 104B | 102.74 GiB | 2.00 GiB | 105.82 GiB | 13.22 GiB | 20±26.5% |
| Mistral-Medium-3.5-128B | Q6_K_L | 128B | 101.13 GiB | 2.75 GiB | 104.93 GiB | 14.11 GiB | 20±26.5% |
Speed is modeled, not measured: decode is memory-bandwidth bound, so tokens per second is bytes read per token against achievable bandwidth. Mixture-of-experts models carry a wider band because only the routed experts are read each step, and few have been measured publicly.
Measured on this card
| Workload◍ | Median | Middle 50% | Runs |
|---|---|---|---|
| Image generation | 11.55 it/s | 8.33–15.62 | 6 |
Aggregated from community-submitted runs, so the spread is wide by nature — it covers different models, resolutions, step counts and settings, not one controlled configuration. Read the middle 50% rather than the median alone. These figures are reproduced with attribution from vladmandic-sd-data-benchmark, which publishes no licence — so we display and link rather than redistribute them.
Questions people ask
- What AI models can a Instinct MI250X run?
- 2091 of 2118 indexed open-weight models fit a Instinct MI250X at 8,192 context with f16 KV cache, the largest being MiMo-V2-Flash at I1-IQ3_XS. That covers text, vision-language, image, video and speech models.
- How much usable memory does a Instinct MI250X actually have?
- Its nameplate is 128 GB, but about 119.04 GiB is available to a model once driver and compositor overhead is accounted for.
- Is a Instinct MI250X fast for local AI?
- Its memory bandwidth is 3277 GB/s, and that figure — not teraflops — is what governs token generation speed. Capacity decides what you can run; bandwidth decides how fast it runs.